Cura Well Plan

Cancer guide

Lung cancer

By Cura Editorial Team ·

The leading cause of cancer death in the US — early detection with low-dose CT and biomarker-driven treatment have changed the outlook dramatically.

What to know first

  • Low-dose CT screening is recommended for adults 50–80 with a significant smoking history.
  • Biomarker testing (EGFR, ALK, ROS1, KRAS, PD-L1) is now standard.
  • About 10–20% of lung cancers occur in people who never smoked.

When to see a doctor

  • A cough that lasts more than 3 weeks or changes character
  • Coughing up blood, even once
  • Unexplained shortness of breath, chest pain, or weight loss

What's new in lung cancer treatment (2026)

Recent approvals and trial results — and the questions to ask your oncologist about whether any of it applies to you. Not every option fits every person.

New option for EGFR-mutant lung cancer

The FDA granted accelerated approval to Datroway for advanced EGFR-mutant lung cancer that grew after EGFR-targeted therapy and chemotherapy.

May apply to: EGFR-mutant advanced non-small cell lung cancer, previously treated

Ask your oncologist:

  • Has my tumor been tested for EGFR?
  • If my current treatment stops working, is Datroway an option?

Source: FDA

New pill for ROS1-positive lung cancer

The FDA approved zidesamtinib (Jideytro) for advanced ROS1-positive lung cancer after at least one prior ROS1-targeted drug.

May apply to: ROS1-positive advanced non-small cell lung cancer

Ask your oncologist:

  • Was ROS1 included in my biomarker testing?
  • What would my next step be if my first targeted pill stops working?

Source: FDA

Reviewed September 25, 2026.

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Frequently asked questions

What are the early warning signs of lung cancer?

The signs that most often lead to a lung cancer diagnosis are: a cough that lasts more than 3 weeks or changes character; coughing up blood, even once; unexplained shortness of breath, chest pain, or weight loss. Any of these lasting more than a couple of weeks is worth a same-week appointment, even though most turn out to be something else.

When should I see a doctor about possible lung cancer?

See a doctor promptly if a symptom is new, persistent, or getting worse rather than better. Describe when it started, how often it happens, and what makes it better or worse — that detail is what decides whether you get imaging or testing at the first visit.

What should I know first about lung cancer?

The leading cause of cancer death in the US — early detection with low-dose CT and biomarker-driven treatment have changed the outlook dramatically. Low-dose CT screening is recommended for adults 50–80 with a significant smoking history. Biomarker testing (EGFR, ALK, ROS1, KRAS, PD-L1) is now standard. About 10–20% of lung cancers occur in people who never smoked.

What questions should I ask after a lung cancer diagnosis?

Ask what the exact diagnosis is and how it is staged, what the treatment options are and in what order they would happen, what the goal of treatment is, which side effects to expect, and whether a second opinion or clinical trial makes sense for your situation.

Related guides

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Before the first treatment decision

If a start date is on the calendar, or you feel lost between diagnosis and the first infusion, build a first-visit brief on the page: what's known, what's missing, what to ask. Homework, not a treatment plan.

Cura Brief is educational. It is not medical advice, a diagnosis, or a treatment plan. Confirm everything with your oncology team. If this is an emergency, call emergency services. Email is not an emergency line.

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After your biopsy or test

Waiting for results is its own kind of hard. Cura has a plain-language guide to what the wait actually means — and what to do while you wait.

How long do biopsy results take?