Cura Well Plan

Cancer guide

Ovarian cancer

By Cura Editorial Team ·

Often called silent, but the symptoms are real and specific — bloating, pelvic pressure, and feeling full fast. BRCA and HRD testing now shape treatment for almost every patient.

What to know first

  • There is no reliable screening test — symptom awareness is the earliest signal.
  • BRCA1/2 and HRD (homologous recombination deficiency) testing determines PARP-inhibitor eligibility.
  • A gynecologic oncologist (not a general gyn) should lead surgery — outcomes are meaningfully better.

When to see a doctor

  • Persistent bloating, pelvic or abdominal pain lasting more than 2–3 weeks
  • Feeling full quickly or a new change in appetite
  • Urinary urgency or frequency without an infection

What's new in ovarian cancer treatment (2026)

Recent approvals and trial results — and the questions to ask your oncologist about whether any of it applies to you. Not every option fits every person.

Keytruda for PD-L1-positive, platinum-resistant ovarian cancer

Based on the phase 3 KEYNOTE-B96 trial, the FDA approved pembrolizumab with chemotherapy for platinum-resistant ovarian cancer that tests PD-L1-positive.

May apply to: Platinum-resistant, PD-L1-positive ovarian cancer

Ask your oncologist:

  • Has my tumor been tested for PD-L1?
  • Would adding Keytruda help in my situation?

Source: FDA

Relacorilant extended survival in a trial

In the phase 3 ROSELLA trial, relacorilant (Lifyorli) with chemotherapy lowered the risk of death by 35% in platinum-resistant ovarian cancer; no biomarker test is required.

May apply to: Platinum-resistant ovarian, fallopian tube, or peritoneal cancer

Ask your oncologist:

  • Is relacorilant an option for me?
  • How would it fit with my current chemotherapy?

Source: Corcept Therapeutics

Reviewed September 25, 2026.

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Frequently asked questions

What are the early warning signs of ovarian cancer?

The signs that most often lead to a ovarian cancer diagnosis are: persistent bloating, pelvic or abdominal pain lasting more than 2–3 weeks; feeling full quickly or a new change in appetite; urinary urgency or frequency without an infection. Any of these lasting more than a couple of weeks is worth a same-week appointment, even though most turn out to be something else.

When should I see a doctor about possible ovarian cancer?

See a doctor promptly if a symptom is new, persistent, or getting worse rather than better. Describe when it started, how often it happens, and what makes it better or worse — that detail is what decides whether you get imaging or testing at the first visit.

What should I know first about ovarian cancer?

Often called silent, but the symptoms are real and specific — bloating, pelvic pressure, and feeling full fast. BRCA and HRD testing now shape treatment for almost every patient. There is no reliable screening test — symptom awareness is the earliest signal. BRCA1/2 and HRD (homologous recombination deficiency) testing determines PARP-inhibitor eligibility. A gynecologic oncologist (not a general gyn) should lead surgery — outcomes are meaningfully better.

What questions should I ask after a ovarian cancer diagnosis?

Ask what the exact diagnosis is and how it is staged, what the treatment options are and in what order they would happen, what the goal of treatment is, which side effects to expect, and whether a second opinion or clinical trial makes sense for your situation.

Related guides

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Before the first treatment decision

If a start date is on the calendar, or you feel lost between diagnosis and the first infusion, build a first-visit brief on the page: what's known, what's missing, what to ask. Homework, not a treatment plan.

Cura Brief is educational. It is not medical advice, a diagnosis, or a treatment plan. Confirm everything with your oncology team. If this is an emergency, call emergency services. Email is not an emergency line.

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After your biopsy or test

Waiting for results is its own kind of hard. Cura has a plain-language guide to what the wait actually means — and what to do while you wait.

How long do biopsy results take?