Cura Well Plan

Cancer guide

Lymphoma

By Cura Editorial Team ·

A large family of blood cancers — exact subtype changes everything, and many indolent lymphomas are watched rather than treated right away.

What to know first

  • Dozens of subtypes with very different treatment paths.
  • 'B symptoms' — drenching sweats, fevers, weight loss — matter for staging.
  • Watch-and-wait is standard care for many indolent (slow-growing) subtypes.

When to see a doctor

  • A painless swollen lymph node that lasts more than 2–4 weeks
  • Drenching night sweats that soak sheets
  • Unexplained fevers or weight loss

What's new in lymphoma cancer treatment (2026)

Recent approvals and trial results — and the questions to ask your oncologist about whether any of it applies to you. Not every option fits every person.

Nivolumab added to first treatment for Hodgkin lymphoma

The FDA approved nivolumab with AVD chemotherapy for newly diagnosed advanced Hodgkin lymphoma after the SWOG S1826 trial showed better progression-free survival.

May apply to: Stage III/IV classical Hodgkin lymphoma, age 12+

Ask your oncologist:

  • Is nivolumab-AVD right for my stage?
  • How does it compare with the older regimen for side effects?

Source: FDA

Epkinly combination for relapsed follicular lymphoma

The FDA approved epcoritamab (Epkinly) with rituximab and lenalidomide for follicular lymphoma that returned or didn't respond, based on the EPCORE FL-1 trial.

May apply to: Relapsed or refractory follicular lymphoma

Ask your oncologist:

  • If my lymphoma comes back, is Epkinly an option?
  • Could CAR-T be given as an outpatient at this center?

Source: FDA

Reviewed September 25, 2026.

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Frequently asked questions

What are the early warning signs of lymphoma cancer?

The signs that most often lead to a lymphoma cancer diagnosis are: a painless swollen lymph node that lasts more than 2–4 weeks; drenching night sweats that soak sheets; unexplained fevers or weight loss. Any of these lasting more than a couple of weeks is worth a same-week appointment, even though most turn out to be something else.

When should I see a doctor about possible lymphoma cancer?

See a doctor promptly if a symptom is new, persistent, or getting worse rather than better. Describe when it started, how often it happens, and what makes it better or worse — that detail is what decides whether you get imaging or testing at the first visit.

What should I know first about lymphoma cancer?

A large family of blood cancers — exact subtype changes everything, and many indolent lymphomas are watched rather than treated right away. Dozens of subtypes with very different treatment paths. 'B symptoms' — drenching sweats, fevers, weight loss — matter for staging. Watch-and-wait is standard care for many indolent (slow-growing) subtypes.

What questions should I ask after a lymphoma cancer diagnosis?

Ask what the exact diagnosis is and how it is staged, what the treatment options are and in what order they would happen, what the goal of treatment is, which side effects to expect, and whether a second opinion or clinical trial makes sense for your situation.

Related guides

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Before the first treatment decision

If a start date is on the calendar, or you feel lost between diagnosis and the first infusion, build a first-visit brief on the page: what's known, what's missing, what to ask. Homework, not a treatment plan.

Cura Brief is educational. It is not medical advice, a diagnosis, or a treatment plan. Confirm everything with your oncology team. If this is an emergency, call emergency services. Email is not an emergency line.

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After your biopsy or test

Waiting for results is its own kind of hard. Cura has a plain-language guide to what the wait actually means — and what to do while you wait.

How long do biopsy results take?